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Chunk #151 — 3 Inverse solutions — 3.1 Non parametric optimization methods — 3.1.1 The Bayesian framework — Spatio-temporal modelling

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Review on solving the inverse problem in EEG source analysis.
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Apart from imposing temporal smoothness constraints, Galka et. al. [35] solved the inverse problem by recasting it as a spatio-temporal state space model which they solve by using Kalman filtering. The computational complexity of this approach that arises due to the high dimensionality of the state vector was addressed by decomposing the model into a set of coupled low-dimensional problems requiring a moderate computational effort. The initial state estimates for the Kalman filter are provided by LORETA. It is shown that by choosing appropriate dynamical models, better solutions than those obtained by the instantaneous inverse solutions (such as LORETA) are obtained.