Chunk #14 — ONLINE METHODS — Variance explained

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New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism.

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To estimate the percentage of variation in birth weight explained jointly by the 7 confirmed birth weight loci, we obtained the adjusted-R2 from univariate linear regression of birth weight against risk allele count in 6 non-European studies and one European study (NFBC1986).