the individual abused other drugs such as cocaine or heroin) or with medical complications such as liver cirrhosis and the Wernicke–Korsakoff syndrome or alcoholic cases with concomitant diseases were excluded. Samples were taken by qualified pathologists under full ethical clearance from the Sydney South West Area Health Service Human Ethics Committee (X03-0117) and informed written consent from the next of kin, kept at −80°C and shipped to Sweden on dry ice.