network and the mendelian protein network were quantified. To assess the probability that the number of connections between the 2 networks was more than would be expected by chance, we performed random simulations with 1000 control networks characterized by the same number of seeds as the Coloc protein network. Control networks were built by using random combinations of seed genes sampled out of the pool of 118 genes characterized by evidence against colocalization in the Coloc analysis (PPH3 > 0.75).
