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Chunk #18 — GENETIC RISK FACTORS FOR AUD IN AI/AN — Genetically influenced predictors for AUD — Exploratory methods for identifying genetic influences on AUD: Linkage analysis

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Review: Genetic and environmental risk factors for alcohol use disorders in American Indians and Alaskan Natives.
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was also associated with anxiety disorders in the Plains American Indians and AUD in the US Caucasians.48 Interestingly, the chromosome 5q13-14 CRHBP location was close to a linkage peak for alcohol craving in Southwest California Indians.49 The CRHBP gene has subsequently been associated with several stress-related disorders in different ethnic groups.50 Other linkage findings for resting EEG, particularly alpha power, in different chromosomal regions in the Southwest California Indian population are reviewed elsewhere.47