These cognitive dimensions of depression inherit a number of questions that are clinically important and remain unresolved, such as (A) the longitudinal course of cognitive deficits in MDD, (B) the relationship between cognitive deficits and general functioning, and (C) the question how social cognitive deficits relate to cognitive function deficits in domains, such as memory, attention, and executive function. To address these questions in more depth will help provide an understanding as to the clinical course and etiology of depression, identifying treatment targets of depression more clearly, and will contribute to clinical prevention.