To explore the full range of published GWAS, we performed a comprehensive independent search for studies not gathered in the Catalog. For each of the 28 diseases, we mined three resources: (i) the PubMed database of biomedical literature, (ii) the HuGE Navigator tool available at the Human Genome Epidemiology Network [41] and (iii) specific reviews available in the literature. Specifically, we searched the PubMed to identify potential new GWAS (i.e. “Asthma AND genome-wide”) and the “HuGE Literature Finder” available at the HuGE Navigator. Finally, we used the PubMed (“Review” tool in Article types) to identify 59 reviews covering the literature available for each disease (∼2.4 reviews per disease). After examination of all these sources, we complemented the list of 277 GWAS with six new genome-wide studies performed on Europeans that had remained unnoticed in the Catalog (Tables S2 and S3).
