false positive findings. Meta-analysis was performed to derive the combined p values between European-American discovery sample and Australians using the program METAL. An overall z-statistic and p-value for each SNP were calculated from a weighted sum of the individual statistics. Weights were proportional to the square-root of the number of individuals examined in each sample and selected such that the squared weights sum to 1.0. For these meta-analysis results, the genome-wide Bonferroni-corrected α was set at 5×10−8 (by one million markers) and the region- and cohort-wide corrected α was set at 1.7×10−5 (by 139 effective markers; see Table S25).
