The 2001–2002 National Epidemiological Survey of Alcohol and Related Conditions (NESARC) surveyed a representative sample of the U.S. population [18]. The target population was the civilian non-institutionalized population 18 years and older residing in households and group quarters (e.g., college quarters, group homes, boarding houses, and non-transient hotels). The survey included residents of the continental United States, District of Columbia, Alaska and Hawaii. Face-to-face computer-assisted interviews were conducted among a multistage cluster sample of 43,093 respondents. Theoverall survey response rate was 81%. Blacks, Hispanics, and adults aged 18–24 were oversampled, with data adjusted for oversampling, household- and person-level non-response [18]. This report examined data of the subsample of respondents with lifetime history of dependence on nicotine (n=6,937), alcohol (n=4,781), cannabis (n=530) or cocaine (n=408).