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Chunk #35 — Online Methods — Quality assessment

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Analysis of protein-coding genetic variation in 60,706 humans.
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for insertions and deletions (indels). Lastly, we compared 13 representative Non-Finnish European exomes included in the call set with their corresponding 30x PCR-Free genome. The overall SNV and indel FDR was 0.14% and 4.71%, while for SNV singletons was 0.389%. The overall FDR by annotation classes missense, synonymous and protein truncating variants (including indels) were 0.076%, 0.055% and 0.471% respectively (Supplementary Information Table 5 and 6). Full details of quality assessments are described in the Supplementary Information Section 1.6.