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Chunk #8 — Measures — Statistical considerations

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Predictors of relapse in a bupropion trial for smoking cessation in recently-abstinent alcoholics: preliminary results using an aggregate genetic risk score.
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As is typical for event occurrence data, our main outcome variable—number of days until relapse—was not normally distributed. Specifically, data obtained for this measure were found to be zero-inflated (due to those participants who did not stop smoking) and right censored (14.6% of observations were censored due to limited assessments over time that did not characterize relapse in all participants). Thus, survival methods were used to examine predictors of risk to relapse.