Chunk #23 — Simulation Study

Source

Consistent Estimation in Mendelian Randomization with Some Invalid Instruments Using a Weighted Median Estimator.

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The status of a genetic variant as an invalid IV is determined by a random draw for each variant. The probability of being an invalid variant is taken as 0.1, 0.2, and 0.3. We consider cases with 10,000 and 20,000 participants.