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Chunk #42 — 4. Discussion

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Random Forest Classification of Alcohol Use Disorder Using EEG Source Functional Connectivity, Neuropsychological Functioning, and Impulsivity Measures.
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among 12 highly significant connections (11 of 12 connections, p ≤ 0.001) (Figure 6), where parahippocampal connections with other DMN regions were predominant (13 connections overall; six highly significant connections). On the other hand, four prefrontal connections of PFC and ACC with other right-hemispheric regions (IPL, LTC, and PHG) had hypoconnectivity and were represented in delta (three connections) and beta bands (1 connection) (Figure 5, panels a–e). Further, the AUD group also showed poor memory performance and increased impulsivity. Identified features from all three domains had significant associations with one another and with AUD status. The interpretations and implications of each of these findings are discussed below.