The alterations in neurobiological organization and behavior seen during adolescence appear to have been notably conserved during evolution with a number of similarities seen across mammalian species (see [16]). It has been suggested to encompass the entire second decade of life (10-20 yrs) in humans [16]. In the rat it has been suggested that the periadolescent period may, as a conservative estimate, span postnatal days 28-42 [17-19].
