In conclusion, in this study we linked the cerebral dynamics observed through EEG and fMRI, for investigating the different contribution of distinct cortical networks to target detection. It is our opinion that the analysis of single trials, as supported by this study, may provide information beyond what can be revealed by the analysis of trial averages. This information can be potentially valuable, mostly when applied to the trial-by-trial coupling of concurrent electrophysiological and hemodynamic cerebral measures, for further investigations on cognitive functions related to sensory processing, attention and memory.