The expression of many of these genes showed expected patterns in the Allen Developing Mouse Brain Atlas (http://developingmouse.brain-map.org/). At E13.5 and E15.5, SST RNA is expressed in a pattern indicative of interneurons in active tangential migration (Figure 6Ba,b). By E18.5 and P4, SST is expressed sparsely in the cortex (Figure 6Bc,d). At P56 (Figure 6Be), SST expression is most prevalent in layers IV-VI. CORT expression was not observed until P4, with a sparse expression pattern reminiscent of interneurons at P56 (Figure 6Bi, j). At P4, RAB3B is present in the intermediate zone and olfactory bulb (Figure 6Bn), and in a pattern resembling SST expression at P56 (Figure 6Bo). This data validates our observations, and suggests that some of these genes are expressed in a pattern indicating they have a role in interneuron maturation and/or function.
