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Chunk #12 — Materials and Methods — Data Analysis

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Association of markers in the 3' region of the GluR5 kainate receptor subunit gene to alcohol dependence.
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Single marker analysis was conducted using logistic regressions in which the predictor included ancestry and coded genotypes for each candidate SNP. We employed an additive model, that is, we coded the three genotypes at a candidate SNP with values of –1, 0, and 1 in the logistic regression analyses.