We next asked whether the result we observed at the age 25 follow-up was already apparent earlier in life. We examined summary measures of participants’ self-reported delinquency, problem alcohol use, and problem cannabis use across an 8-year window spanning grade 7 through two years post-high school. Analyses were limited to the European-American subsample. Parallel to results at age 25 follow-up, Fast Track intervention was associated with lower levels of delinquency, alcohol use, and cannabis use during the adolescent period for rs10482672 “A” carriers; for non-carriers of the “A” allele, the intervention had no effect (for delinquency, δ=−0.034, p=0.00200; for alcohol, δ=−4.165, p= 0.00185; for cannabis, δ=−2.390, p= 0.00714). Complete model results are reported in Appendix Tables A3 and A4xii.
