This longitudinal analysis using responses obtained retrospectively during the research interviews found that current and past tobacco use are significant independent predictors over a 3-year period of a future suicide attempt. This finding is in line with two previous reports [18,21], but contradicts two other studies [13,19]. Tobacco use status changes exerted predictive effects on suicide attempt. Relapse to tobacco use and initiation of tobacco use were strongly associated with suicide attempt. However, former tobacco use status both at Wave 1 and Wave 2 was not associated with increased suicide attempt risk. DSM-IV nicotine dependence did not predict a suicide attempt during Wave 2.