Chunk #55 — Methods — Follow-Up in Independent GIANT Consortium Samples (GIANT Stage 2) — Meta-analysis of all GIANT data (stage 1+stage 2)

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Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution.

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Five of the 26 loci that were selected for follow up show nominal evidence of association with both WC and WHR (TFAP2B (rs987237) was one of these). However, for none of these loci did the association with WHR reach genome-wide significance in the overall, combined analysis (Table S2).