Many prior studies have found an association of current smoking and suicide (Leistikow & Shipley 1999). In addition, a recent review cited some evidence that smoking cessation could precipitate a clinical depression (Hughes 2006) and, thus, might lead to increased suicide. Thirdly, a recently published study (Nissen et al. 2008) and data analyses from regulatory agencies (US Food and Drug Administration 2008; US Food and Drug Administration 2007b) suggested bupropion, rimonabant and varenicline--medications marketed for or developed for smoking cessation--are associated with suicide (US Food and Drug Administration 2007b; US Food and Drug Administration 2007a).
