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Chunk #37 — Discussion

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International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci.
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case-control studies showing elevations of immune-related biomarkers in women with PTSD49, and epigenetic studies pointing to the role of the immune system in PTSD etiology50,51. Further work is needed to determine whether PTSD has genetic overlap with immune disorders broadly and the causal direction between disorders. At minimum, the emerging genetic evidence presented here suggests that association between PTSD and health conditions may, in some cases, have some genetic origin.