and Buzsaki, 1996; Kawaguchi and Kondo, 2002; Kawaguchi and Kubota, 1998; Klausberger and Somogyi, 2008; Markram et al., 2004; Monyer and Markram, 2004; Mott and Dingledine, 2003; Somogyi and Klausberger, 2005; Somogyi et al., 1998). We are thus facing a discrepancy between the vast and detailed knowledge of inhibitory mechanisms and properties and our limited understanding of how these mechanisms and properties play together to contribute to cortical function. In other words, we now have more details about interneurons than we know what to do with. A clear example of this discrepancy has been the spectacular and still ongoing characterization of the many types of cortical inhibitory interneurons on one hand and our very poor understanding of what each type contributes to cortical processing on the other hand.
