PTSD genomic profiles assess the degree of genetic propensity, in probabilistic terms, for developing PTSD following a traumatic experience. This information is of great importance not only for identifying biomarkers for disease prognosis, but also for elucidating disease etiology and mechanisms. As genetic profiles can be obtained prior to trauma exposure, they can also be used to plan preventative measures in at-risk populations, including military personnel. For example, duty assignments, number of tours, and dwell times between tours can be adjusted in relation to risk and resilience profiles. Pre-deployment resilience building strategies and personalized early interventions can also be implemented, especially for those that are at a higher risk. Furthermore, in the long-term, enhanced understanding of the genetics of the disorder will inform the design and tailoring of effective therapeutics.
