This study used data from both waves of the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC). The nationally representative 2001-2002 Wave 1 sample contained 43,093 U.S. adults 18 and older living in households and noninstitutional group quarters (response rate = 81.0%). The 2004-2005 Wave 2 follow-up sample contained 34,653 of the original respondents, 86.7% of those eligible for reinterview, for a cumulative response rate of 70.2%. Detailed information on the sample design and weighting are available elsewhere (Grant et al., 2003a, 2007, 2009). All potential respondents were informed in writing about the nature of the survey, uses of the survey data, voluntary nature of their participation and legally-mandated confidentiality of identifiable survey information. The research protocol received full ethical review and approval from the U.S. Census Bureau and the U.S. Office of Management and Budget.