differences in route, alcohol-dosing procedures (single bolus vs. cumulative dosing), and maximum BAC reached. Some prior studies have used the intravenous route and peak BAC levels are often less than 0.08%. The current study used oral alcohol administration, as this is the route in the natural environment. We also targeted a maximum BAC of 0.1% over 2 hours of drinking to mimic BAC reached during binge drinking. The higher BAC in the current study may be relevant for the greater sedative and aversive effects of alcohol, as detected by the SHAS and DEQ VAS, when compared to lower BAC achieved in some studies.
