Chunk #9 — Results

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A Brief Critique of the TATES Procedure.

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We used simulation-based methods to test the critical assumption that the pdf of the TATES p-value distribution is <=1 around 0. In our first simulation example, the TATES statistic was based on normal phenotypes. The number of effective phenotypes ranged between 1.28 and 1.98, and was estimated in R using the formula defined in van der Sluis et al. (2013).