Data are presented throughout as the mean ± SEM. Statistical analyses were performed using Prism 6 or 7 (GraphPad Software, Inc.; La Jolla, CA). Data were analyzed with Student’s two-tailed t-test, 1-way ANOVA, 2-way ANOVA, or 2-way ANOVA with repeated measures, as appropriate. Tukey, Holm-Sidak, Dunnett’s, and Bonferroni multiple comparison post hoc tests were used, if justified. Differences were considered significant if P < 0.05.
