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Chunk #2 — Introduction

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Heritability of level of response and association with recent drinking history in nonalcohol-dependent drinkers.
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Many of the characteristics that influence LR also have an effect on recent drinking history (RDH) in terms of number of alcohol drinks (quantity), the lifetime maximum number of drinks consumed (Schuckit et al, 2006), and number of alcohol drinks per drinking occasion. Males, for instance may consume more alcohol, more often, than females (Schuckit et al., 2007; Pedersen and McCarthy, 2009). Body weight may influence quantity and frequency of drinks (Schuckit et al., 2005b; Schuckit et al., 2006) with lower body weight participants consuming less alcohol, less often. FHA alone, however, may not have any effect on the quantity, drinks per drinking occasion, or frequency of drinks consumed (deWit and McCracken, 1990). The interaction of gender, FHA, and body weight, with low LR may produce higher quantity (Schuckit et al., 2006) and drinks per drinking occasion among individuals with low LR, and vice versa among those with high LR.