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Chunk #23 — Future Directions

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Developmental Endophenotypes: Indexing Genetic Risk for Substance Abuse with the P300 Brain Event-Related Potential.
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instance, self-harm behavior, which is more common among female adolescents than males, clearly represents a form of disinhibited behavior. Borderline personality disorder also shares key features with externalizing. Indeed, P3AR has been observed among adolescents with borderline personality (Houston, Bauer, & Hesselbrock, 2004). In sum, resolving inconsistencies between genders might lead both to more refined endophenotypes and to more refined conceptualizations of disorders.