Genes differentially expressed at FDR = 0.1 were uploaded into Ingenuity Pathway Analysis (Ingenuity Systems, www.ingenuity.com). Genes were identified by their Affymetrix probe set ID and then mapped to their corresponding objects in the Ingenuity Knowledge Base. These molecules, called Network Eligible molecules, were overlaid onto a global molecular network developed from information contained in the Ingenuity Knowledge Base. Networks of Network Eligible Molecules were then algorithmically generated based on their connectivity.
