AD history is negatively associated with reproduction among women, in particular. In Cohort I, 64% (n = 98) of alcoholic (AD+) women reported biological children, compared to 78% (n = 2699) of non-alcoholic (AD-) women [χ2 (df) = 16.12 (1), p <.0001]. Fifty-nine percent (n = 195) of AD+ men compared to 69% (n = 1069) of AD− men reported biological children [χ2 (df) = 10.92 (1), p <.001]. In Cohort II, 38% (n = 196) of AD+ women reported biological children, compared to 49% (n = 1403) of AD− women [χ2 (df) = 23.52 (1), p <.0001]. A roughly equivalent proportion of AD+ and AD- men reported biological children in Cohort II —36% (n = 300) of AD+ men and 38% (n = 730) of AD− men [χ2 (df) = 1.78 (1), p =.18].