The studies included a range of phenotypes, including heroin addiction, opioid dependence (OD); heroin-induced subjective response; cocaine addiction/dependence (CD); alcohol dependence (AD), methamphetamine (MAP) dependence/psychosis (MD); amphetamine-induced euphoria; response to alcohol; adolescent alcohol misuse; antisocial drug dependence in adolescents; response to naltrexone (NTX) treatment; and personality traits. For review of association studies of MAP use disorders see (Bousman et al. 2009).