We selected a subset of genetically uncorrelated traits for each SNP (used in Extended Data Figure 6, Table 2, and Supplementary Table 15), aiming to select traits from a diverse a set of groups as possible (anthropometric, lipids/metabolic, blood, cardiovascular/metabolic disease, other; Extended Data Figure 6, Supplementary Table 8). To this aim, we iterated over trait groups cyclically. For each group containing ≥1 unselected traits with PIP>0.95 for the analyzed SNP, we selected the trait having the smallest average |rg| with unselected traits from other groups (if there remained any) or from all remaining traits (otherwise), selecting among all traits having |rg|<0.2 with previously selected traits, until no more eligible traits remained. We plotted the ideogram in Extended Data Figure 6 with the PhenoGram63 software.
