Chunk #15 — Materials and Methods — Smoking-related diseases — Chronic obstructive pulmonary disease

Source

A rare missense mutation in CHRNA4 associates with smoking behavior and its consequences.

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United Kingdom A total of 206 subjects with COPD defined by spirometry (forced expiratory volume (FEV)/forced vital capacity (FVC) <0.7, FEV1% <80%), over 40 years of age, and 338 controls, as part of the Nottingham Smokers Study.25