activity during resting-state in BD. Furthermore, SL alpha deficits were most prominent in pairwise clusters comprising a subnetwork (Fig. 4) that included the frontal (F4), fronto-central (FC3 and FC4), central (Cz), and centro-parietal (CPz) regions. Decreased functional connectivity was greater over the right hemisphere (F4 and FC4), consistent with a frequent findings of asymmetric alpha band activity in emotional processing and mood disorders (Coan and Allen, 2004). Together, our results demonstrate a breakdown of functional connectivity at rest that likely reflects disrupted information processing and functional integration in BD.
