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Chunk #31 — Results — Behavioral Performance

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Novelty P3 reductions in depression: characterization using principal components analysis (PCA) of current source density (CSD) waveforms.
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Participants performed well on this task (98.5 ± 1.9 total% correct). Only one healthy participant and five depressed patients performed at less than 95%. Nontarget performance was close to perfect for both groups (controls: 99.6 ± 0.6; patients: 99.5 ± 0.8), and the correct rejection of novels was comparable for the two groups (controls: 96.6 ± 4.3; patients: 96.4 ± 4.2). Patients had significantly longer reaction times to targets compared to controls (491 ± 87 ms vs. 438 ± 88 ms), F(1,97) = 8.84, p = .004, a difference that was preserved when age was used as a covariate, F(1,97) = 5.62, p = .02.