In addition to the primary outcome phenotypes, several demographic measures were collected (Table S1). We examined the correlations between these demographic measures and the outcome phenotypes. We observed strong correlations between age, gender, and BMI and multiple response measures (Figure S1). Notably, we did not see strong correlations between current or past drug use and any of the response measurements in this sample of light drug users. For each outcome phenotype we derived a corrected phenotype by taking the residuals of a linear regression model, using age, sex and BMI as covariates.
