One neuropathologist (I.K.) examined, in a blind-to-diagnosis fashion, on average 120 hemispheric CV-stained sections per case with a 1.2-mm distance between sections. Two-step screening included examination at low magnification (28×) using Zeiss DL2 Documator and microscopic examination using objective lenses from 5× to 100×. Two other neuropathologists (T.W. and J.W.) examined all histological slides for which pathology was detected during the primary screening. The defects of neurogenesis, neuronal migration, and dysplastic changes that they detected were summarized in this report.
