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Chunk #59 — Discussion — Effects of decision conflict and alcohol

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Event-Related Theta Power during Lexical-Semantic Retrieval and Decision Conflict is Modulated by Alcohol Intoxication: Anatomically Constrained MEG.
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cortex. This strongly converges with our observation that theta power was elicited by real words in the left-lateralized language system. In contrast, the activity in a more bilateral lateral prefrontal and medial ACC network was modulated by increased difficulty demands in both our study, and the Sabsevitz et al. study. These convergent findings suggest that different neurofunctional networks contribute to successful performance in an interactive and flexible manner, as they are sensitive to the semantic dimension, but also rely on more general functions such as attention, working memory, response monitoring, and optimization, etc. (Noppeney et al., 2004; Binder et al., 2009). Consequently, moderate alcohol intoxication impairs semantic retrieval and decreases the efficiency of controlled processing. It also affects response preparation and execution, as reflected in weaker theta power in hand-centered motor areas under intoxication.