Chunk #6 — Methods — Ethics statement

Source

Decitabine alters the expression of Mecp2 isoforms via dynamic DNA methylation at the Mecp2 regulatory elements in neural stem cells.

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All experiments were performed in accordance with the standards of the Canadian Council on Animal Care with the approval of the Office of Research Ethics of University of Manitoba. All experimental procedures were reviewed and approved (protocol number 12–031) by the University of Manitoba Bannatyne Campus Protocol Management and Review Committee.