However, in certain situations it may be possible to disentangle the etiology of imperfect CGRs to some extent. For instance, in case one considers a specific phenotype that is usually studied by means of a commonly available but relatively heterogeneous and/or noisy measure, while there also exists a less readily available but more accurate and homogeneous measure. If one has access to both these measures in several studies, one can compare the CGR estimates for the more accurate measure and the CGR estimates for the less accurate but more commonly available measure. Such a comparison would help to disentangle the contribution of phenotypic heterogeneity and genetic heterogeneity to the CGR of the more commonly available measure.
