Asp40 carriers consumed a higher number of drinks, and urge to drink was less strongly associated with number of drinks consumed among carriers of the Asp40 allele within a given drinking episode. In short, these post-hoc analyses suggest that Urge to Drink may be a less potent determinant of drinking behavior among Asp40 carriers. There was no other genotype (i.e., OPRM1 or DRD4) × subjective response (i.e., Vigor or Urge to Drink) interaction with regard to alcohol consumption assessed via morning report.