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Chunk #34 — Discussion — Interaction of life events and 5-HTTLPR in the two genders

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Financial difficulties but not other types of recent negative life events show strong interactions with 5-HTTLPR genotype in the development of depressive symptoms.
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behaviour in women, and with aggression, conduct disorder and externalising behaviours in men.63 Gender differences in the effects of 5-HTTLPR were also reported in functional imaging65 and resting-state electroencephalogram studies.66 Specifically, greater synchronisation of regional neural organisation and the modulation of EEG activity in a wide frequency range was found in s-carrier women contributing to gender differences in cognition and emotion as well as affective states.66