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Chunk #18 — Results — Heterogeneity in Variance Components, by Age

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Heritability of cardiovascular and personality traits in 6,148 Sardinians.
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To look for heterogeneity in variance components by age, we divided individuals into two groups. The “younger” group included individuals less than 42 y of age (the median age in our sample), whereas the “older” group included individuals 42 y of age and older. We found significant evidence for heterogeneity in variance components by age in 62 of the 98 traits examined (the results are summarized in Table 4). This included a majority of traits in all categories, including anthropometric traits (three of five), blood test results (24 of 38), cardiovascular traits (13 of 20), and personality factors and facets (22 of 35). Again, we considered a series of intermediate models, including only heterogeneity in environmental or genetic variance components, or in which variance components differed by a constant factor between the young and old, and used the BIC to select the best-fitting model. For 26 traits, a model in which only the environmental variance differed between young and old was selected, and for 20 of these traits, environmental variance was greater among older individuals (so that heritability was lower). Heritability was higher in older individuals for IMT and five personality traits.