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Chunk #17 — RESULTS — ALDH2 Analyses

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ALDH2 and ADH1B interactions in retrospective reports of low-dose reactions and initial sensitivity to alcohol in Asian American college students.
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The bottom portion of Table 1 shows the means and standard deviations for total symptoms and SRE_5 across ALDH2 genotype. Total symptoms significantly differed across ALDH2 genotypes (F = 186.09, 2/761 df, p < .001), with post-hoc analyses indicating all three genotypes significantly differed from one another (Tukey HSD p‘s < .001). Individuals with two ALDH2*2 alleles endorsed the highest average number of symptoms (3.74) followed by those with one ALDH2*2 allele (2.05) and those with no ALDH2*2 alleles (0.73). SRE_5 also significantly differed across ALDH2 genotype (F = 43.15, 2/732 df, p < .001). Post-hoc analyses indicated individuals with no ALDH2*2 alleles had significantly higher SRE_5 scores (3.38) than individuals with one (2.22) and two (1.65) ALDH2*2 alleles (Tukey HSD p’s < .001).