MOAFTS and MOFAM assessments were nearly identical by design to facilitate integration of data across studies (with adjustments for differences in ascertainment strategies). In both studies, data were collected via telephone interview by trained interviewers using a modified version of the Semi-Structured Assessment for the Genetics of Alcoholism (SSAGA; Bucholz et al., 1994). The SSAGA was designed to assess substance use history, psychiatric disorders, and other related psychosocial domains. Other than the wave 5 MOAFTS interview, which covered the 2 years between Wave 4 and 5 assessments, interviews queried lifetime psychiatric and psychosocial history.