Given a list of SNPs and P-values from a statistical test for genetic association, the goal of the GIN prioritization method (4) is to combine biological information with evidence for genetic association to prioritize SNPs for further study so that SNPs with biologically relevant properties receive higher priority. This is done by first specifying a non-negative prioritization score for each SNP. If S is the GIN prioritization score, the weighted P-value Pw is defined by Pw = P/10S (4–5). SNPs are ranked for further study by Pw where smaller values of Pw have higher priority.
