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Chunk #18 — INITIAL ENIGMA‐EEG FINDINGS — Follow‐up inquiries into the genetic contributions to EEG

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Large-scale collaboration in ENIGMA-EEG: A perspective on the meta-analytic approach to link neurological and psychiatric liability genes to electrophysiological brain activity.
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expression. This suggests that hippocampal GABRA2 expression affects beta oscillations and may be linked to the pivotal role hippocampal GABA plays in habit‐forming and reward processing in alcohol dependence (Enoch, 2008). Interestingly, this is in line with ongoing work by ENIGMA's Addiction working group; a fine‐scale morphometric analysis alcohol dependence was associated with abnormalities in a range of structures, but showed the strongest effects in the hippocampus (Chye et al., 2020), as well as in the thalamus, putamen, and amygdala.