Chunk #29 — Neurocognitive and Brain Functional Response Systems and Their Operational Relationships to the Undercontrol/Disinhibition Developmental Pathway
In summary, there is ample evidence of important development in regulatory abilities and the neural networks that support those abilities during the period from childhood to early adolescence, as well as into early adulthood. Experiential moderators during this period also affect network development. Alcohol consumption in adolescence may also impede development, but current evidence is insufficient to regard this as a firm conclusion. The current behavioral and imaging data also converge in suggesting that frontostriatal-thalamic and limbic networks involved in regulatory control and motivation are also involved in key temperament/personality domains bearing on the development of undercontrol and the regulation of SUD risk. This work strongly suggests that there will be individual differences in neural network functionality between high- and low-undercontrol individuals. This hypothesis needs to be evaluated.
